EMD-27732

Single-particle
4.1 Å
EMD-27732
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Deposition: 28/07/2022
Map released: 02/11/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27732
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eEF1A(GDP)aa-tRNA stalled on the rabbit 80S ribosome by ternatin-4

EMD-27732

Single-particle
4.1 Å
EMD-27732
3D View Gallery
Deposition: 28/07/2022
Map released: 02/11/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus
Sample: eEF1A(GDP)aa-tRNA stalled on the rabbit 80S ribosome by ternatin-4

Deposition Authors: Brown A , Shao S , Rundlet EJ , Juette MF , Carelli JD , Taunton J , Blanchard SC
Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.
Juette MF , Carelli JD , Rundlet EJ , Brown A , Shao S , Ferguson A, Wasserman MR, Holm M, Taunton J , Blanchard SC
(2022) eLife , 11
PUBMED: 36264623
DOI: doi:10.7554/eLife.81608
ISSN: 2050-084X