EMD-27694

Single-particle
3.2 Å
EMD-27694
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Deposition: 25/07/2022
Map released: 26/10/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27694
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eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by ternatin-4

EMD-27694

Single-particle
3.2 Å
EMD-27694
3D View Gallery
Deposition: 25/07/2022
Map released: 26/10/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli, Homo sapiens, Oryctolagus cuniculus
Sample: eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by ternatin-4

Deposition Authors: Rundlet EJ , Ferguson A, Juette MF , Carelli JD , Taunton J , Blanchard SC
Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.
Juette MF , Carelli JD , Rundlet EJ , Brown A , Shao S , Ferguson A, Wasserman MR, Holm M, Taunton J , Blanchard SC
(2022) eLife , 11
PUBMED: 36264623
DOI: doi:10.7554/eLife.81608
ISSN: 2050-084X