EMD-27691

Single-particle
3.6 Å
EMD-27691
3D View Gallery
Deposition: 25/07/2022
Map released: 26/10/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27691
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by didemnin B

EMD-27691

Single-particle
3.6 Å
EMD-27691
3D View Gallery
Deposition: 25/07/2022
Map released: 26/10/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli, Homo sapiens, Oryctolagus cuniculus
Sample: eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by didemnin B

Deposition Authors: Rundlet EJ , Juette MF , Blanchard SC , Ferguson A, Taunton J , Carelli JD
Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.
Juette MF , Carelli JD , Rundlet EJ , Brown A , Shao S , Ferguson A, Wasserman MR, Holm M, Taunton J , Blanchard SC
(2022) eLife , 11
PUBMED: 36264623
DOI: doi:10.7554/eLife.81608
ISSN: 2050-084X