EMD-27691

Single-particle
3.6 Å
EMD-27691
3D View Gallery
Deposition: 25/07/2022
Map released: 26/10/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27691

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by didemnin B

EMD-27691

Single-particle
3.6 Å
EMD-27691
3D View Gallery
Deposition: 25/07/2022
Map released: 26/10/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli, Homo sapiens, Oryctolagus cuniculus
Sample: eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by didemnin B

Deposition Authors: Rundlet EJ , Juette MF , Blanchard SC , Ferguson A, Taunton J , Carelli JD
Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.
Juette MF , Carelli JD , Rundlet EJ , Brown A , Shao S , Ferguson A, Wasserman MR, Holm M, Taunton J , Blanchard SC
(2022) eLife , 11
PUBMED: 36264623
DOI: doi:10.7554/eLife.81608
ISSN: 2050-084X