EMD-27490

Single-particle
3.39 Å
EMD-27490
3D View Gallery
Deposition: 05/07/2022
Map released: 21/09/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27490

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8dkm summary report (pdf.gz) Map-8dkm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of cystine-bound cystinosin in a lumen-open state

EMD-27490

Single-particle
3.39 Å
EMD-27490
3D View Gallery
Deposition: 05/07/2022
Map released: 21/09/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Cystinosin-Fab 3H5 complex with cystine bound in a lumen-open conformation
Fitted models: 8dkm

Deposition Authors: Schmiege P , Li X
Structure and mechanism of human cystine exporter cystinosin.
Guo X, Schmiege P , Assafa TE , Wang R , Xu Y, Donnelly L, Fine M, Ni X, Jiang J, Millhauser G, Feng L, Li X
(2022) Cell , 185 , 3739 - 3752.e18
PUBMED: 36113465
DOI: doi:10.1016/j.cell.2022.08.020
ISSN: 1097-4172