EMD-27408

Single-particle
3.45 Å
EMD-27408
3D View Gallery
Deposition: 22/06/2022
Map released: 29/03/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27408

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8dfm summary report (pdf.gz) Map-8dfm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Ectodomain of full-length wild-type KIT-SCF dimers

EMD-27408

Single-particle
3.45 Å
EMD-27408
3D View Gallery
Deposition: 22/06/2022
Map released: 29/03/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Full-length wild-type KIT-SCF dimers reconstituted in amphipol
Fitted models: 8dfm

Deposition Authors: Krimmer SG , Bertoletti N , Mi W , Schlessinger J
Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Krimmer SG , Bertoletti N , Suzuki Y , Katic L , Mohanty J, Shu S, Lee S , Lax I, Mi W , Schlessinger J
(2023) PNAS , 120 , e2300054120 - e2300054120
PUBMED: 36943885
DOI: doi:10.1073/pnas.2300054120
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: