EMD-27221

Single-particle
3.54 Å
EMD-27221
3D View Gallery
Deposition: 06/06/2022
Map released: 29/03/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27221

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8d6a summary report (pdf.gz) Map-8d6a FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM map of human LIF signaling complex with full extracellular domains

EMD-27221

Single-particle
3.54 Å
EMD-27221
3D View Gallery
Deposition: 06/06/2022
Map released: 29/03/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human LIF in complex with gp130 and LIFR
Fitted models: 8d6a

Deposition Authors: Zhou Y , Franklin MC
Structural insights into the assembly of gp130 family cytokine signaling complexes.
Zhou Y , Stevis PE, Cao J, Saotome K, Wu J , Glatman Zaretsky A , Haxhinasto S , Yancopoulos GD, Murphy AJ , Sleeman MW , Olson WC, Franklin MC
(2023) Sci Adv , 9 , eade4395 - eade4395
PUBMED: 36930708
DOI: doi:10.1126/sciadv.ade4395
ISSN: 2375-2548
Grant Support: