EMD-27081
IMM20184 and IMM20253 Fabs in ternary complex with SARS-CoV-2 receptor binding domain
EMD-27081
Single-particle4.0 Å
Deposition: 24/05/2022Map released: 08/06/2022
Last modified: 21/09/2022
Sample Organism:
Severe acute respiratory syndrome coronavirus,
Homo sapiens
Sample: IMM20184 and IMM20253 Fabs in ternary complex with RBD of SARS-CoV-2
Deposition Authors: Robinson MK, Nikitin PN
Sample: IMM20184 and IMM20253 Fabs in ternary complex with RBD of SARS-CoV-2
Deposition Authors: Robinson MK, Nikitin PN
IMM-BCP-01, a patient-derived anti-SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA.1 and BA.2.
Nikitin PA 
,
DiMuzio JM ,
Dowling JP ,
Patel NB ,
Bingaman-Steele JL ,
Heimbach BC ,
Henriquez N ,
Nicolescu C ,
Polley A ,
Sikorski EL,
Howanski RJ,
Nath M ,
Shukla H,
Scheaffer SM,
Finn JP,
Liang LF ,
Smith T,
Storm N ,
McKay LGA ,
Johnson RI ,
Malsick LE ,
Honko AN,
Griffiths A ,
Diamond MS ,
Sarma P ,
Geising DH ,
Morin MJ,
Robinson MK
(2022) Sci Immunol , 7 , eabl9943 - eabl9943
,
DiMuzio JM ,
Dowling JP ,
Patel NB ,
Bingaman-Steele JL ,
Heimbach BC ,
Henriquez N ,
Nicolescu C ,
Polley A ,
Sikorski EL,
Howanski RJ,
Nath M ,
Shukla H,
Scheaffer SM,
Finn JP,
Liang LF ,
Smith T,
Storm N ,
McKay LGA ,
Johnson RI ,
Malsick LE ,
Honko AN,
Griffiths A ,
Diamond MS ,
Sarma P ,
Geising DH ,
Morin MJ,
Robinson MK
(2022) Sci Immunol , 7 , eabl9943 - eabl9943
Grant Support:
- Other private: (United States)