EMD-27028

Single-particle
2.84 Å
EMD-27028
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Deposition: 19/05/2022
Map released: 15/03/2023
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27028
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8cwo summary report (pdf.gz) Map and 8cwo FULL report (pdf.gz)
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Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, body domain only in the local refined map

EMD-27028

Single-particle
2.84 Å
EMD-27028
3D View Gallery
Deposition: 19/05/2022
Map released: 15/03/2023
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Cutibacterium acnes, Escherichia coli
Sample: 30S subunit body domain from 70S ribosome with mRNA, P-site tRNA and Sarecycline bound
Fitted models: 8cwo

Deposition Authors: Lomakin IB , Devarkar SC , Bunick CG
Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Lomakin IB , Devarkar SC , Patel S, Grada A , Bunick CG
(2023) Nucleic Acids Res , 51 , 2915 - 2930
PUBMED: 36864821
DOI: doi:10.1093/nar/gkad103
ISSN: 1362-4962
ASTM: NARHAD
Grant Support: