EMDB EMD-2677

Single particle reconstruction
4.5Å resolution

Three-dimensional structure of human gamma-secretase at 4.5 angstrom resolution

Map released:
Last modified:
Overview of EMD-2677
Source organism: Homo sapiens [9606]
Fitted atomic model: 4upc
Related EM entry by publication: EMD-2678
Primary publication:
Three-dimensional structure of human gamma-secretase
Lu PL, Bai XC, Ma D, Xie T, Yan CY, Sun LF, Yang GH, Zhao YY, Zhou R, Scheres SHW, Shi YG
NATURE 512 166-170 (2014)
PMID: 25043039

Function and Biology Details

Sample name: human gamma-secretase
Protein: human gamma-secretase

Experimental Information Details

Resolution: 4.5Å
Resolution method: FSC 0.143, gold-standard
Applied symmetry: C1
Reconstruction software: CTFFIND3, RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)