EMD-26685

Helical reconstruction
3.47 Å
EMD-26685
3D View Gallery
Deposition: 19/04/2022
Map released: 03/05/2023
Last modified: 13/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26685
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8e7e summary report (pdf.gz) Map and 8e7e FULL report (pdf.gz)
EMICSS annotations (xml)

Cardiac amyloid fibrils extracted from a variant ATTR I84S amyloidosis patient

EMD-26685

Helical reconstruction
3.47 Å
EMD-26685
3D View Gallery
Deposition: 19/04/2022
Map released: 03/05/2023
Last modified: 13/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: cardiac amyloid fibril of variant I84S transthyretin amyloidosis
Fitted models: 8e7e

Deposition Authors: Nguyen BA , Saelices L
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy
Nguyen BA , Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pekala M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L
(2024) Nat Commun , 15 , 581
DOI: doi:10.1038/s41467-024-44820-3
ISSN: 2041-1723