EMD-26665

Helical reconstruction
3.8 Å
EMD-26665
3D View Gallery
Deposition: 15/04/2022
Map released: 28/09/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26665
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7upg summary report (pdf.gz) Map and 7upg FULL report (pdf.gz)
EMICSS annotations (xml)

Tau Paired Helical Filament from Alzheimer's Disease incubated with EGCG for 3 hours

EMD-26665

Helical reconstruction
3.8 Å
EMD-26665
3D View Gallery
Deposition: 15/04/2022
Map released: 28/09/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Tau Paired Helical Filament from Alzheimer's Disease incubated with EGCG for 3 hours
Fitted models: 7upg

Deposition Authors: Seidler PM, Murray KA, Boyer DR , Ge P , Sawaya MR , Eisenberg DS
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Seidler PM, Murray KA, Boyer DR , Ge P , Sawaya MR , Hu CJ , Cheng X, Abskharon R, Pan H , DeTure MA, Williams CK, Dickson DW , Vinters HV, Eisenberg DS
(2022) Nat Commun , 13 , 5451 - 5451
PUBMED: 36114178
DOI: doi:10.1038/s41467-022-32951-4
ISSN: 2041-1723