EMD-26664

Helical reconstruction
3.3 Å
EMD-26664
3D View Gallery
Deposition: 15/04/2022
Map released: 28/09/2022
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26664
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7upf summary report (pdf.gz) Map and 7upf FULL report (pdf.gz)
EMICSS annotations (xml)

Tau Paired Helical Filament from Alzheimer's Disease incubated 1 hr. with EGCG

EMD-26664

Helical reconstruction
3.3 Å
EMD-26664
3D View Gallery
Deposition: 15/04/2022
Map released: 28/09/2022
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Tau Alzheimer's Disease Paired Helical Filament incubated 1 hr. with EGCG
Fitted models: 7upf

Deposition Authors: Seidler PM, Murray KA, Boyer DR , Ge P , Sawaya MR , Eisenberg DS
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Seidler PM, Murray KA, Boyer DR , Ge P , Sawaya MR , Hu CJ , Cheng X, Abskharon R, Pan H , DeTure MA, Williams CK, Dickson DW , Vinters HV, Eisenberg DS
(2022) Nat Commun , 13 , 5451 - 5451
PUBMED: 36114178
DOI: doi:10.1038/s41467-022-32951-4
ISSN: 2041-1723