EMD-26663

Helical reconstruction
3.4 Å
EMD-26663
3D View Gallery
Deposition: 15/04/2022
Map released: 28/09/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26663
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7upe summary report (pdf.gz) Map and 7upe FULL report (pdf.gz)
EMICSS annotations (xml)

Tau Paired Helical Filament from Alzheimer's Disease not incubated with EGCG

EMD-26663

Helical reconstruction
3.4 Å
EMD-26663
3D View Gallery
Deposition: 15/04/2022
Map released: 28/09/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Tau Paired Helical Filament from Alzheimer's Disease not incubated with EGCG
Fitted models: 7upe

Deposition Authors: Seidler PM, Murray KA, Boyer DR , Ge P , Sawaya MR , Eisenberg DS
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Seidler PM, Murray KA, Boyer DR , Ge P , Sawaya MR , Hu CJ , Cheng X, Abskharon R, Pan H , DeTure MA, Williams CK, Dickson DW , Vinters HV, Eisenberg DS
(2022) Nat Commun , 13 , 5451 - 5451
PUBMED: 36114178
DOI: doi:10.1038/s41467-022-32951-4
ISSN: 2041-1723