EMD-26588

Single-particle
3.4 Å
EMD-26588
3D View Gallery
Deposition: 02/04/2022
Map released: 25/05/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26588

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human NKCC1 K289NA492E Bound with Furosemide

EMD-26588

Single-particle
3.4 Å
EMD-26588
3D View Gallery
Deposition: 02/04/2022
Map released: 25/05/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: hNKCC1-Furosemide complex

Deposition Authors: Zhao Y , Cao E
Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide
Zhao Y , Roy K, Vidossich P, Cancedda L, De Vivo M, Forbush B, Cao E
(2022) Nat Commun , 13 , 2747
DOI: doi:10.1038/s41467-022-30407-3
ISSN: 2041-1723
Grant Support: