EMD-26409

Single-particle
2.58 Å
EMD-26409
3D View Gallery
Deposition: 11/03/2022
Map released: 03/08/2022
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26409

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7u9x summary report (pdf.gz) Map-7u9x FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of PKA phosphorylated human RyR2-R2474S in the closed state

EMD-26409

Single-particle
2.58 Å
EMD-26409
3D View Gallery
Deposition: 11/03/2022
Map released: 03/08/2022
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of RyR2-R2474S and Calstabin-2
Fitted models: 7u9x

Deposition Authors: Miotto MC , Marks AR
Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Miotto MC , Weninger G , Dridi H , Yuan Q, Liu Y , Wronska A , Melville Z , Sittenfeld L , Reiken S , Marks AR
(2022) Sci Adv , 8 , eabo1272 - eabo1272
PUBMED: 35857850
DOI: doi:10.1126/sciadv.abo1272
ISSN: 2375-2548