Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-26286
TMEM106B(120-254) doublet amyloid fibril from progressive supranuclear palsy (PSP) case 2.
EMD-26286
Helical reconstruction3.6 Å
Deposition: 20/02/2022Map released: 20/04/2022
Last modified: 27/04/2022
Sample Organism:
Homo sapiens
Sample: TMEM106B(120-254) singlet amyloid fibril from dementia with Lewy bodies (DLB).
Deposition Authors: Chang A
,
Xiang X ,
Wang J,
Lee C,
Arakhamia T,
Simjanoska M,
Wang C,
Carlomagno Y,
Zhang G,
Dhingra S,
Thierry M,
Perneel J ,
Heeman B ,
Forgrave LM,
DeTure M,
DeMarco ML ,
Cook CN,
Rademakers R,
Dickson D,
Petrucelli L,
Stowell MHB,
Mackenzie IRA,
Fitzpatrick AWP
Sample: TMEM106B(120-254) singlet amyloid fibril from dementia with Lewy bodies (DLB).
Deposition Authors: Chang A
,
Xiang X ,
Wang J,
Lee C,
Arakhamia T,
Simjanoska M,
Wang C,
Carlomagno Y,
Zhang G,
Dhingra S,
Thierry M,
Perneel J ,
Heeman B ,
Forgrave LM,
DeTure M,
DeMarco ML ,
Cook CN,
Rademakers R,
Dickson D,
Petrucelli L,
Stowell MHB,
Mackenzie IRA,
Fitzpatrick AWP
Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Chang A ,
Xiang X ,
Wang J,
Lee C,
Arakhamia T,
Simjanoska M,
Wang C,
Carlomagno Y,
Zhang G,
Dhingra S,
Thierry M,
Perneel J ,
Heeman B ,
Forgrave LM,
DeTure M,
DeMarco ML ,
Cook CN,
Rademakers R,
Dickson DW,
Petrucelli L,
Stowell MHB,
Mackenzie IRA,
Fitzpatrick AWP
(2022) Cell , 185 , 1346 - 1355.e15
,
Xiang X ,
Wang J,
Lee C,
Arakhamia T,
Simjanoska M,
Wang C,
Carlomagno Y,
Zhang G,
Dhingra S,
Thierry M,
Perneel J ,
Heeman B ,
Forgrave LM,
DeTure M,
DeMarco ML ,
Cook CN,
Rademakers R,
Dickson DW,
Petrucelli L,
Stowell MHB,
Mackenzie IRA,
Fitzpatrick AWP
(2022) Cell , 185 , 1346 - 1355.e15
Grant Support: