EMD-26191

Single-particle
8.5 Å
EMD-26191
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Deposition: 14/02/2022
Map released: 11/05/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26191
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Cryo-EM structure of human SARM1 TIR domain in complex with 1AD

EMD-26191

Single-particle
8.5 Å
EMD-26191
3D View Gallery
Deposition: 14/02/2022
Map released: 11/05/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Active state assembly of hSARM1-TIR domain with 1AD.

Deposition Authors: Saikot FK , Kobe B , Ve T , Nanson JD , Gu W, Luo Z, Brillault L, Landsberg MJ
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.
Shi Y , Kerry PS, Nanson JD , Bosanac T, Sasaki Y, Krauss R, Saikot FK , Adams SE, Mosaiab T, Masic V, Mao X, Rose F, Vasquez E, Furrer M, Cunnea K, Brearley A, Gu W, Luo Z, Brillault L, Landsberg MJ , DiAntonio A, Kobe B , Milbrandt J, Hughes RO, Ve T
(2022) Mol Cell , 82 , 1643 - 1659.e10
PUBMED: 35334231
DOI: doi:10.1016/j.molcel.2022.03.007
ISSN: 1097-2765
ASTM: MOCEFL