Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-26125

Single-particle
2.9 Å
EMD-26125
3D View Gallery
Deposition: 02/02/2022
Map released: 06/07/2022
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26125
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7ttw summary report (pdf.gz) Map and 7ttw FULL report (pdf.gz)
EMICSS annotations (xml)

50S ribosomal subunit from Staphylococcus aureus containing double mutation in uL3 imparting linezolid resistance

EMD-26125

Single-particle
2.9 Å
EMD-26125
3D View Gallery
Deposition: 02/02/2022
Map released: 06/07/2022
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Staphylococcus aureus
Sample: 50S ribosomal subunit from Staphylococcus aureus - double mutation in uL3 leading to linezolid resistance
Fitted models: 7ttw

Deposition Authors: Belousoff MJ , Piper S
A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid.
Perlaza-Jimenez L, Tan KS, Piper SJ, Johnson RM, Bamert RS, Stubenrauch CJ, Wright A, Lupton D, Lithgow T , Belousoff MJ
(2022) Microbiol Spectr , 10 , e0058322 - e0058322
PUBMED: 35736238
DOI: doi:10.1128/spectrum.00583-22
ISSN: 2165-0497