EMD-26082

Single-particle
3.6 Å
EMD-26082
3D View Gallery
Deposition: 28/01/2022
Map released: 10/08/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26082
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7tr8 summary report (pdf.gz) Map and 7tr8 FULL report (pdf.gz)
EMICSS annotations (xml)

Cascade complex from type I-A CRISPR-Cas system

EMD-26082

Single-particle
3.6 Å
EMD-26082
3D View Gallery
Deposition: 28/01/2022
Map released: 10/08/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Pyrococcus furiosus DSM 3638, Geobacter sulfurreducens, Escherichia coli
Sample: Cas3 bound Cascade complex from Pyrococcus furiosus type I-A CRISPR/Cas system
Fitted models: 7tr8

Deposition Authors: Hu C , Ni D
Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Hu C , Ni D, Nam KH , Majumdar S , McLean J, Stahlberg H , Terns MP, Ke A
(2022) Mol Cell , 82 , 2754 - 2768.e5
PUBMED: 35835111
DOI: doi:10.1016/j.molcel.2022.06.007
ISSN: 1097-2765
ASTM: MOCEFL