EMD-25709

Single-particle
4.0 Å
EMD-25709
3D View Gallery
Deposition: 13/12/2021
Map released: 20/07/2022
Last modified: 28/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25709

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7t64 summary report (pdf.gz) Map-7t64 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state

EMD-25709

Single-particle
4.0 Å
EMD-25709
3D View Gallery
Deposition: 13/12/2021
Map released: 20/07/2022
Last modified: 28/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus, Homo sapiens
Sample: Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state
Fitted models: 7t64

Deposition Authors: Iyer KA , Hu Y, Murayama T , Samso M
Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Iyer KA , Hu Y, Klose T , Murayama T , Samso M
(2022) PNAS , 119 , e2122140119 - e2122140119
PUBMED: 35867837
DOI: doi:10.1073/pnas.2122140119
ISSN: 1091-6490
ASTM: PNASA6