EMD-25688
CryoEM structure of 2x HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and 2x neutralizing fabs 8I21 and 13H11
EMD-25688
Single-particle3.84 Å
Deposition: 10/12/2021Map released: 23/03/2022
Last modified: 17/01/2024
Sample Organism:
Human betaherpesvirus 5,
Homo sapiens
Sample: Complex of 2x HCMV Pentamer proteins gH, gL, UL128, UL130, UL131A bound to Neuropilin 2 and 2x fabs of human neutralizing antibodies 8I21 and 13H11
Deposition Authors: Kschonsak M
,
Johnson MC ,
Schelling R ,
Green EM ,
Rouge L ,
Ho H ,
Patel N ,
Kilic C,
Kraft E ,
Arthur CP ,
Rohou AL ,
Comps-Agrar L ,
Martinez-Martin N,
Perez L ,
Payandeh J ,
Ciferri C
Sample: Complex of 2x HCMV Pentamer proteins gH, gL, UL128, UL130, UL131A bound to Neuropilin 2 and 2x fabs of human neutralizing antibodies 8I21 and 13H11
Deposition Authors: Kschonsak M
,
Johnson MC ,
Schelling R ,
Green EM ,
Rouge L ,
Ho H ,
Patel N ,
Kilic C,
Kraft E ,
Arthur CP ,
Rohou AL ,
Comps-Agrar L ,
Martinez-Martin N,
Perez L ,
Payandeh J ,
Ciferri C
Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Kschonsak M ,
Johnson MC ,
Schelling R ,
Green EM ,
Rouge L ,
Ho H ,
Patel N ,
Kilic C,
Kraft E ,
Arthur CP ,
Rohou AL ,
Comps-Agrar L ,
Martinez-Martin N,
Perez L ,
Payandeh J ,
Ciferri C
(2022) Sci Adv , 8 , eabm2536 - eabm2536
,
Johnson MC ,
Schelling R ,
Green EM ,
Rouge L ,
Ho H ,
Patel N ,
Kilic C,
Kraft E ,
Arthur CP ,
Rohou AL ,
Comps-Agrar L ,
Martinez-Martin N,
Perez L ,
Payandeh J ,
Ciferri C
(2022) Sci Adv , 8 , eabm2536 - eabm2536
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