EMD-25687

Single-particle
3.1 Å
EMD-25687
3D View Gallery
Deposition: 10/12/2021
Map released: 23/03/2022
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25687

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7t4s summary report (pdf.gz) Map-7t4s FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and neutralizing fabs 8I21 and 13H11

EMD-25687

Single-particle
3.1 Å
EMD-25687
3D View Gallery
Deposition: 10/12/2021
Map released: 23/03/2022
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human betaherpesvirus 5, Homo sapiens
Sample: Pentameric complex of HCMV proteins gH, gL, UL128, UL130, UL131A bound to Neuropilin 2 and fabs of human neutralizing antibodies 8I21 and 13H11
Fitted models: 7t4s

Deposition Authors: Kschonsak M , Johnson MC
Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Kschonsak M , Johnson MC , Schelling R, Green EM, Rouge L , Ho H , Patel N , Kilic C, Kraft E , Arthur CP , Rohou AL, Comps-Agrar L , Martinez-Martin N, Perez L , Payandeh J , Ciferri C
(2022) Sci Adv , 8 , eabm2536 - eabm2536
PUBMED: 35275719
DOI: doi:10.1126/sciadv.abm2536
ISSN: 2375-2548
Grant Support: