EMD-25445

Single-particle
3.8 Å
EMD-25445
3D View Gallery
Deposition: 18/11/2021
Map released: 12/01/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25445
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7sv7 summary report (pdf.gz) Map and 7sv7 FULL report (pdf.gz)
EMICSS annotations (xml)

The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)

EMD-25445

Single-particle
3.8 Å
EMD-25445
3D View Gallery
Deposition: 18/11/2021
Map released: 12/01/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)
Fitted models: 7sv7

Deposition Authors: Fiedorczuk K, Chen J
Mechanism of CFTR correction by type I folding correctors.
Fiedorczuk K, Chen J
(2022) Cell , 185 , 158 - 168.e11
PUBMED: 34995514
DOI: doi:10.1016/j.cell.2021.12.009
ISSN: 1097-4172
Grant Support: