EMD-25174

Single-particle
4.0 Å
EMD-25174
3D View Gallery
Deposition: 19/10/2021
Map released: 27/07/2022
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25174

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7sk6 summary report (pdf.gz) Map-7sk6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of human ACKR3 in complex with chemokine N-terminal mutant CXCL12_LRHQ and an intracellular Fab

EMD-25174

Single-particle
4.0 Å
EMD-25174
3D View Gallery
Deposition: 19/10/2021
Map released: 27/07/2022
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex structure of ACKR3-CXCL12_LRHQ- CID24
Fitted models: 7sk6

Deposition Authors: Yen YC , Schafer CT
Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Yen YC , Schafer CT , Gustavsson M , Eberle SA , Dominik PK, Deneka D , Zhang P , Schall TJ, Kossiakoff AA, Tesmer JJG , Handel TM
(2022) Sci Adv , 8 , eabn8063 - eabn8063
PUBMED: 35857509
DOI: doi:10.1126/sciadv.abn8063
ISSN: 2375-2548