EMD-25133

Single-particle
9.1 Å
EMD-25133
3D View Gallery
Deposition: 11/10/2021
Map released: 04/05/2022
Last modified: 22/06/2022
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25133

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Androgen receptor bound to DNA - Splayed state

EMD-25133

Single-particle
9.1 Å
EMD-25133
3D View Gallery
Deposition: 11/10/2021
Map released: 04/05/2022
Last modified: 22/06/2022
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Androgen receptor bound to DNA - Splayed state

Deposition Authors: Wasmuth EV, Vanden Broeck A, Klinge S, Sawyers CL
Allosteric interactions prime androgen receptor dimerization and activation.
Wasmuth EV, Broeck AV, LaClair JR, Hoover EA, Lawrence KE, Paknejad N, Pappas K, Matthies D, Wang B, Feng W, Watson PA, Zinder JC , Karthaus WR , de la Cruz MJ, Hite RK, Manova-Todorova K, Yu Z, Weintraub ST, Klinge S, Sawyers CL
(2022) Mol Cell , 82 , 2021 - 2031.e5
PUBMED: 35447082
DOI: doi:10.1016/j.molcel.2022.03.035
ISSN: 1097-2765
ASTM: MOCEFL