EMD-24963

Single-particle
5.9 Å
EMD-24963
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Deposition: 23/09/2021
Map released: 15/12/2021
Last modified: 15/12/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24963
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Mouse retromer (VPS26/VPS35/VPS29) heterotrimer in the presence of cyclic peptide RTL4

EMD-24963

Single-particle
5.9 Å
EMD-24963
3D View Gallery
Deposition: 23/09/2021
Map released: 15/12/2021
Last modified: 15/12/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Mouse retromer (VPS26/VPS35/VPS29) heterotrimer in the presence of cyclic peptide RTL4

Deposition Authors: Kendall AK , Jackson LP
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Chen KE , Guo Q , Hill TA , Cui Y, Kendall AK , Yang Z , Hall RJ , Healy MD , Sacharz J, Norwood SJ, Fonseka S , Xie B , Reid RC , Leneva N , Parton RG , Ghai R, Stroud DA , Fairlie DP , Suga H, Jackson LP , Teasdale RD , Passioura T , Collins BM
(2021) Sci Adv , 7 , eabg4007 - eabg4007
PUBMED: 34851660
DOI: doi:10.1126/sciadv.abg4007
ISSN: 2375-2548