Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-24871

Single-particle
3.1 Å
EMD-24871
3D View Gallery
Deposition: 13/09/2021
Map released: 17/11/2021
Last modified: 17/11/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24871
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

CryoEM map of modular PKS holo-Lsd14 bound to antibody fragment 1B2, focused refinement of LDAT domains

EMD-24871

Single-particle
3.1 Å
EMD-24871
3D View Gallery
Deposition: 13/09/2021
Map released: 17/11/2021
Last modified: 17/11/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Streptomyces lasalocidi
Sample: Dimeric holo-Lsd14 containing docking domains from DEBS module 3 (holo-Lsd14-DD*) bound to two copies each of Fab 1B2 light and heavy chains and NADP.

Deposition Authors: Bagde SR , Kim C-Y, Fromme JC
Modular polyketide synthase contains two reaction chambers that operate asynchronously.
Bagde SR , Mathews II , Fromme JC , Kim CY
(2021) Science , 374 , 723 - 729
PUBMED: 34735234
DOI: doi:10.1126/science.abi8532
ISSN: 1095-9203
ASTM: SCIEAS