EMD-24854
Modified BG505 SOSIP-based immunogen RC1 in complex with elicited mAb Ab1170NHP Fab and 8ANC195 Fab
EMD-24854
Single-particle4.5 Å
Deposition: 13/09/2021Map released: 06/04/2022
Last modified: 06/04/2022
Sample Organism:
Macaca mulatta,
Human immunodeficiency virus 1,
Homo sapiens
Sample: Elicited Ab1170NHP Fab in complex with immunogen RC1 SOSIP and bNAb 8ANC195 Fab
Deposition Authors: Abernathy ME
,
Bjorkman PJ
Sample: Elicited Ab1170NHP Fab in complex with immunogen RC1 SOSIP and bNAb 8ANC195 Fab
Deposition Authors: Abernathy ME
,
Bjorkman PJ
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env.
Escolano A ,
Gristick HB ,
Gautam R ,
DeLaitsch AT ,
Abernathy ME ,
Yang Z ,
Wang H ,
Hoffmann MAG ,
Nishimura Y ,
Wang Z ,
Koranda N,
Kakutani LM ,
Gao H,
Gnanapragasam PNP,
Raina H ,
Gazumyan A ,
Cipolla M ,
Oliveira TY ,
Ramos V ,
Irvine DJ ,
Silva M ,
West Jr AP ,
Keeffe JR ,
Barnes CO ,
Seaman MS ,
Nussenzweig MC ,
Martin MA ,
Bjorkman PJ
(2021) Sci Transl Med , 13 , eabk1533 - eabk1533
,
Gristick HB ,
Gautam R ,
DeLaitsch AT ,
Abernathy ME ,
Yang Z ,
Wang H ,
Hoffmann MAG ,
Nishimura Y ,
Wang Z ,
Koranda N,
Kakutani LM ,
Gao H,
Gnanapragasam PNP,
Raina H ,
Gazumyan A ,
Cipolla M ,
Oliveira TY ,
Ramos V ,
Irvine DJ ,
Silva M ,
West Jr AP ,
Keeffe JR ,
Barnes CO ,
Seaman MS ,
Nussenzweig MC ,
Martin MA ,
Bjorkman PJ
(2021) Sci Transl Med , 13 , eabk1533 - eabk1533
Grant Support: