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EMD-2478
Negative stain electron microscopy structure of compound E-bound human Presenilin 1 (PS1) complex
EMD-2478
Single-particle17.4 Å
Deposition: 23/09/2013Map released: 20/11/2013
Last modified: 02/03/2016
Sample Organism:
Homo sapiens,
synthetic construct
Sample: Compound E-bound human Presenilin 1 (PS1) complex
Deposition Authors: Li Y, Lu S, Tsai CJ, Bohm C, Qamar S, Dodd RB
,
Meadows W,
Jeon A,
McLeod A ,
Chen F,
Arimon M ,
Berezovska O,
Hyman BT,
Tomita T ,
Iwatsubod T,
Johnsof CM,
Farrer L,
Schmitt-Ulms G,
Fraser P,
St George-Hyslop P
Sample: Compound E-bound human Presenilin 1 (PS1) complex
Deposition Authors: Li Y, Lu S, Tsai CJ, Bohm C, Qamar S, Dodd RB
,
Meadows W,
Jeon A,
McLeod A ,
Chen F,
Arimon M ,
Berezovska O,
Hyman BT,
Tomita T ,
Iwatsubod T,
Johnsof CM,
Farrer L,
Schmitt-Ulms G,
Fraser P,
St George-Hyslop P
Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes.
Li Y,
Lu SH,
Tsai CJ,
Bohm C,
Qamar S,
Dodd RB ,
Meadows W,
Jeon A,
McLeod A ,
Chen F,
Arimon M ,
Berezovska O,
Hyman BT,
Tomita T ,
Iwatsubo T ,
Johnson CM,
Farrer LA ,
Schmitt-Ulms G,
Fraser PE,
St George-Hyslop PH
(2014) Structure , 22 , 125 - 135
,
Meadows W,
Jeon A,
McLeod A ,
Chen F,
Arimon M ,
Berezovska O,
Hyman BT,
Tomita T ,
Iwatsubo T ,
Johnson CM,
Farrer LA ,
Schmitt-Ulms G,
Fraser PE,
St George-Hyslop PH
(2014) Structure , 22 , 125 - 135