EMD-2477

Single-particle
17.4 Å
EMD-2477
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Deposition: 23/09/2013
Map released: 20/11/2013
Last modified: 17/02/2016
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-2477
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Negative stain electron microscopy structure of native human Presenilin 1 (PS1) complex

EMD-2477

Single-particle
17.4 Å
EMD-2477
3D View Gallery
Deposition: 23/09/2013
Map released: 20/11/2013
Last modified: 17/02/2016
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: native human Presenilin 1 (PS1) complex

Deposition Authors: Li Y, Lu S, Tsai CJ , Bohm C, Qamar S, Dodd RB , Meadows W, Jeon A, McLeod A , Chen F, Arimon M , Berezovska O, Hyman BT, Tomita T , Iwatsubod T, Johnsof CM, Farrer L, Schmitt-Ulms G, Fraser P, St George-Hyslop P
Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes.
Li Y, Lu SH, Tsai CJ , Bohm C, Qamar S, Dodd RB , Meadows W, Jeon A, McLeod A , Chen F, Arimon M , Berezovska O, Hyman BT, Tomita T , Iwatsubo T , Johnson CM, Farrer LA , Schmitt-Ulms G, Fraser PE, St George-Hyslop PH
(2014) Structure , 22 , 125 - 135