EMD-24757

Single-particle
3.3 Å
EMD-24757
3D View Gallery
Deposition: 27/08/2021
Map released: 31/08/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24757
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7rze summary report (pdf.gz) Map and 7rze FULL report (pdf.gz)
EMICSS annotations (xml)

Insulin Degrading Enzyme pO/pC

EMD-24757

Single-particle
3.3 Å
EMD-24757
3D View Gallery
Deposition: 27/08/2021
Map released: 31/08/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cysteine-free Insulin-degrading enzyme in complex with Insulin A chain and Insulin B chain
Fitted models: 7rze

Deposition Authors: Mancl JM , Liang WG

Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
Mancl JM , Liang WG, Wei H, Carragher B, Potter CS, Tang WJ
To Be Published