EMD-24623
Negative stain electron microscopy single particle reconstruction of monoclonal antibody DH950 Fab in complex with HIV-1 Env CH505 SOSIP trimer.
EMD-24623
Single-particle15.4 Å
Deposition: 04/08/2021Map released: 25/08/2021
Last modified: 08/03/2023
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 2,
Human immunodeficiency virus 1
Sample: Complex of HIV Env CH505TFchim.6R.SOSIP.664.v4.1 with DH950 antibody Fab
Deposition Authors: Edwards RJ
,
Mansouri K
Sample: Complex of HIV Env CH505TFchim.6R.SOSIP.664.v4.1 with DH950 antibody Fab
Deposition Authors: Edwards RJ
,
Mansouri K
Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection.
Saunders KO ,
Edwards RJ ,
Tilahun K ,
Manne K ,
Lu X ,
Cain DW ,
Wiehe K ,
Williams WB ,
Mansouri K ,
Hernandez GE ,
Sutherland L ,
Scearce R ,
Parks R ,
Barr M,
DeMarco T,
Eater CM ,
Eaton A ,
Morton G ,
Mildenberg B ,
Wang Y ,
Rountree RW,
Tomai MA,
Fox CB ,
Moody MA ,
Alam SM,
Santra S ,
Lewis MG ,
Denny TN,
Shaw GM ,
Montefiori DC,
Acharya P ,
Haynes BF
(2022) Sci Transl Med , 14 , eabo5598 - eabo5598
,
Edwards RJ ,
Tilahun K ,
Manne K ,
Lu X ,
Cain DW ,
Wiehe K ,
Williams WB ,
Mansouri K ,
Hernandez GE ,
Sutherland L ,
Scearce R ,
Parks R ,
Barr M,
DeMarco T,
Eater CM ,
Eaton A ,
Morton G ,
Mildenberg B ,
Wang Y ,
Rountree RW,
Tomai MA,
Fox CB ,
Moody MA ,
Alam SM,
Santra S ,
Lewis MG ,
Denny TN,
Shaw GM ,
Montefiori DC,
Acharya P ,
Haynes BF
(2022) Sci Transl Med , 14 , eabo5598 - eabo5598
Grant Support: