EMD-24075

Single-particle
4.46 Å
EMD-24075
3D View Gallery
Deposition: 19/05/2021
Map released: 25/05/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24075
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7mxp summary report (pdf.gz) Map and 7mxp FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of NTD-directed neutralizing antibody LP5 Fab in complex with SARS-CoV-2 S2P spike

EMD-24075

Single-particle
4.46 Å
EMD-24075
3D View Gallery
Deposition: 19/05/2021
Map released: 25/05/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus 2
Sample: Prefusion SARS-CoV-2 spike glycoprotein in complex with LP5 Fab
Fitted models: 7mxp

Deposition Authors: Reddem ER , Casner RG
Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS-CoV-2.
Madan B , Reddem ER , Wang P , Casner RG, Nair MS , Huang Y, Fahad AS, de Souza MO, Banach BB, Lopez Acevedo SN , Pan X, Nimrania R, Teng IT, Bahna F, Zhou T, Zhang B, Yin MT , Ho DD, Kwong PD , Shapiro L, DeKosky BJ
(2021) Aiche J , 67 , e17440 - e17440
PUBMED: 34898670
DOI: doi:10.1002/aic.17440
ISSN: 0001-1541
Grant Support: