Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-23838

Single-particle
3.5 Å
EMD-23838 Deposition: 16/04/2021
Map released: 26/05/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23838

Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Map 4

EMD-23838

Single-particle
3.5 Å
EMD-23838 Deposition: 16/04/2021
Map released: 26/05/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae
Sample: Dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound
Fitted models: 7mi3

Deposition Authors: Santarossa CC, Coudray N, Urnavicius L, Ekiert DC, Bhabha G , Kapoor TM
Targeting allostery in the Dynein motor domain with small molecule inhibitors.
PUBMED: 34015309
DOI: doi:10.1016/j.chembiol.2021.04.024
ISSN: 2451-9456