EMD-23808

Single-particle
2.89 Å
EMD-23808
3D View Gallery
Deposition: 08/04/2021
Map released: 14/07/2021
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23808

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7mez summary report (pdf.gz) Map-7mez FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of the phosphoinositide 3-kinase p110 gamma (PIK3CG) p101 (PIK3R5) complex

EMD-23808

Single-particle
2.89 Å
EMD-23808
3D View Gallery
Deposition: 08/04/2021
Map released: 14/07/2021
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Sus scrofa
Sample: Ternary complex of p110 gamma with p101 and a p101 binding nanobody
Fitted models: 7mez

Deposition Authors: Burke JE , Dalwadi U , Rathinaswamy MK , Yip CK
Structure of the phosphoinositide 3-kinase (PI3K) p110 gamma-p101 complex reveals molecular mechanism of GPCR activation.
Rathinaswamy MK , Dalwadi U , Fleming KD , Adams C, Stariha JTB , Pardon E , Baek M , Vadas O , DiMaio F , Steyaert J , Hansen SD , Yip CK , Burke JE
(2021) Sci Adv , 7
PUBMED: 34452907
DOI: doi:10.1126/sciadv.abj4282
ISSN: 2375-2548