EMD-23687

Helical reconstruction
3.9 Å
EMD-23687
3D View Gallery
Deposition: 25/03/2021
Map released: 22/09/2021
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23687
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7m62 summary report (pdf.gz) Map and 7m62 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 2

EMD-23687

Helical reconstruction
3.9 Å
EMD-23687
3D View Gallery
Deposition: 25/03/2021
Map released: 22/09/2021
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: hIAPP fibril
Fitted models: 7m62

Deposition Authors: Cao Q , Boyer DR
Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Cao Q , Boyer DR, Sawaya MR , Abskharon R, Saelices L, Nguyen BA, Lu J, Murray KA, Kandeel F, Eisenberg DS
(2021) Nat Struct Mol Biol , 28 , 724 - 730
DOI: doi:10.1038/s41594-021-00646-x
ISSN: 1545-9985