EMD-23566
The SARS-CoV-2 spike protein receptor binding domain bound to neutralizing nanobodies WNb 2 and WNb 10
EMD-23566
Single-particle3.44 Å
Deposition: 03/03/2021Map released: 05/05/2021
Last modified: 23/10/2024
Sample Organism:
Vicugna pacos,
Severe acute respiratory syndrome coronavirus 2
Sample: Focused refinement of the SARS-CoV-2 spike protein receptor binding domain bound to neutralizing nanobodies WNb 2 and WNb 10
Fitted models: 7lx5
Deposition Authors: Pymm P
,
Glukhova A
Sample: Focused refinement of the SARS-CoV-2 spike protein receptor binding domain bound to neutralizing nanobodies WNb 2 and WNb 10
Fitted models: 7lx5
Deposition Authors: Pymm P
,
Glukhova A
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice.
Pymm P ,
Adair A ,
Chan LJ ,
Cooney JP ,
Mordant FL ,
Allison CC,
Lopez E ,
Haycroft ER ,
O'Neill MT ,
Tan LL ,
Dietrich MH ,
Drew D ,
Doerflinger M ,
Dengler MA ,
Scott NE ,
Wheatley AK ,
Gherardin NA ,
Venugopal H ,
Cromer D ,
Davenport MP ,
Pickering R ,
Godfrey DI,
Purcell DFJ ,
Kent SJ ,
Chung AW ,
Subbarao K ,
Pellegrini M ,
Glukhova A ,
Tham WH
(2021) PNAS , 118
,
Adair A ,
Chan LJ ,
Cooney JP ,
Mordant FL ,
Allison CC,
Lopez E ,
Haycroft ER ,
O'Neill MT ,
Tan LL ,
Dietrich MH ,
Drew D ,
Doerflinger M ,
Dengler MA ,
Scott NE ,
Wheatley AK ,
Gherardin NA ,
Venugopal H ,
Cromer D ,
Davenport MP ,
Pickering R ,
Godfrey DI,
Purcell DFJ ,
Kent SJ ,
Chung AW ,
Subbarao K ,
Pellegrini M ,
Glukhova A ,
Tham WH
(2021) PNAS , 118
Grant Support:
- National Health and Medical Research Council (NHMRC, Australia): GNT2002073 (Australia)
- Wellcome Trust: 208693/Z/17/Z (Australia)