EMD-23462

Single-particle
3.9 Å
EMD-23462
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Deposition: 09/02/2021
Map released: 14/04/2021
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23462
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Structure of CD4 mimetic BNM-III-170 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab

EMD-23462

Single-particle
3.9 Å
EMD-23462
3D View Gallery
Deposition: 09/02/2021
Map released: 14/04/2021
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human immunodeficiency virus 1
Sample: Complex of BG505 SOSIP.664 Env with CD4 mimetic BNM-III-170 and 17b Fab
Fitted models: 7lo6

Deposition Authors: Jette CA , Bjorkman PJ
Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
Jette CA , Barnes CO, Kirk SM, Melillo B , Smith III AB, Bjorkman PJ
(2021) Nat Commun , 12 , 1950 - 1950
PUBMED: 33782388
DOI: doi:10.1038/s41467-021-21816-x
ISSN: 2041-1723