EMDB EMD-23395

Single particle reconstruction
5.0Å resolution

Structure of the SARS-CoV-2 spike trimer in complex with mRNA vaccine induced neutralizing antibody C643

Map released:
Overview of EMD-23395
Primary publication:
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants.
Wang Z, Schmidt F, Weisblum Y, Muecksch F, Barnes CO, Finkin S, Schaefer-Babajew D, Cipolla M, Gaebler C, Lieberman JA, Oliveira TY, Yang Z, Abernathy ME, Huey-Tubman KE, Hurley A, Turroja M, West KA, Gordon K, Millard KG, Ramos V, Silva JD, Xu J, Colbert RA, Patel R, Dizon J, Unson-O'Brien C, Shimeliovich I, Gazumyan A, Caskey M, Bjorkman PJ, Casellas R, Hatziioannou T, Bieniasz PD, Nussenzweig MC
Nature - (2021)
PMID: 33567448

Function and Biology Details

Sample name: SARS-CoV-2 S 6P trimer complexed with monoclonal Fab C601
Proteins: SARS-CoV-2 S 6P trimer complexed with monoclonal Fab C601, SARS-CoV-2 spike glycoprotein 6P trimer, C643 Fab

Experimental Information Details

Resolution: 5.0Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: cryoSPARC
Microscope: FEI TALOS ARCTICA
Detector: OTHER