EMD-23300

Single-particle
3.5 Å
EMD-23300
3D View Gallery
Deposition: 15/01/2021
Map released: 26/01/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23300

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7lf6 summary report (pdf.gz) Map-7lf6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of lysosomal membrane protein

EMD-23300

Single-particle
3.5 Å
EMD-23300
3D View Gallery
Deposition: 15/01/2021
Map released: 26/01/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dimer of a membrane protein
Fitted models: 7lf6

Deposition Authors: Shen C , Fu TM
pH regulates potassium conductance and drives a constitutive proton current in human TMEM175.
Zheng W , Shen C , Wang L , Rawson S , Xie WJ , Nist-Lund C , Wu J , Shen Z, Xia S , Holt JR , Wu H , Fu TM
(2022) Sci Adv , 8 , eabm1568 - eabm1568
PUBMED: 35333573
DOI: doi:10.1126/sciadv.abm1568
ISSN: 2375-2548