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EMD-23160
Prefusion-stabilized SARS-CoV-2 spike bound by the engineered human antibody ADG-2
EMD-23160
Single-particle5.94 Å
Deposition: 19/12/2020Map released: 10/02/2021
Last modified: 03/03/2021
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: Prefusion-stabilized SARS-CoV-2 spike bound by a single copy of ADG-2 Fab
Deposition Authors: Wrapp D, McLellan JS
Sample: Prefusion-stabilized SARS-CoV-2 spike bound by a single copy of ADG-2 Fab
Deposition Authors: Wrapp D, McLellan JS
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody.
Rappazzo CG 
,
Tse LV ,
Kaku CI ,
Wrapp D ,
Sakharkar M ,
Huang D ,
Deveau LM ,
Yockachonis TJ ,
Herbert AS ,
Battles MB ,
O'Brien CM ,
Brown ME ,
Geoghegan JC,
Belk J,
Peng L,
Yang L ,
Hou Y,
Scobey TD,
Burton DR ,
Nemazee D ,
Dye JM ,
Voss JE ,
Gunn BM ,
McLellan JS ,
Baric RS ,
Gralinski LE ,
Walker LM
(2021) Science , 371 , 823 - 829
,
Tse LV ,
Kaku CI ,
Wrapp D ,
Sakharkar M ,
Huang D ,
Deveau LM ,
Yockachonis TJ ,
Herbert AS ,
Battles MB ,
O'Brien CM ,
Brown ME ,
Geoghegan JC,
Belk J,
Peng L,
Yang L ,
Hou Y,
Scobey TD,
Burton DR ,
Nemazee D ,
Dye JM ,
Voss JE ,
Gunn BM ,
McLellan JS ,
Baric RS ,
Gralinski LE ,
Walker LM
(2021) Science , 371 , 823 - 829
Grant Support: