Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-23058

Subtomogram averaging
15.0 Å
EMD-23058
3D View Gallery
Deposition: 02/12/2020
Map released: 13/10/2021
Last modified: 13/10/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23058
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

The stress-sensing domain of activated IRE1a forms helical filaments in narrow ER membrane tubes

EMD-23058

Subtomogram averaging
15.0 Å
EMD-23058
3D View Gallery
Deposition: 02/12/2020
Map released: 13/10/2021
Last modified: 13/10/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Double-helical arrangement of human IRE1a luminal domain in 30 nm ER tubes

Deposition Authors: Carter SD, Tran NH, De Maziere A, Ashkenazi A, Klumpermann J, Walter P, Jensen GJ
The stress-sensing domain of activated IRE1 alpha forms helical filaments in narrow ER membrane tubes.
Tran NH , Carter SD , De Maziere A , Ashkenazi A , Klumperman J , Walter P , Jensen GJ
(2021) Science , 374 , 52 - 57
PUBMED: 34591618
DOI: doi:10.1126/science.abh2474
ISSN: 1095-9203
ASTM: SCIEAS