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EMD-22945
Negative stain electron microscopy reconstruction of neutralizing NTD-directed Fab DH1050.2 in complex with 2P SARS-CoV-2 spike ectodomain
EMD-22945
Single-particle19.3 Å
Deposition: 04/11/2020Map released: 18/11/2020
Last modified: 01/09/2021
Sample Organism:
Severe acute respiratory syndrome coronavirus 2
Sample: Complex of RBD-directed Fab DH1042 with hexapro SARS-CoV-2 spike ectodomain
Deposition Authors: Edwards RJ, Mansouri K
Sample: Complex of RBD-directed Fab DH1042 with hexapro SARS-CoV-2 spike ectodomain
Deposition Authors: Edwards RJ, Mansouri K
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.
Li D,
Edwards RJ 
,
Manne K,
Martinez DR,
Schafer A,
Alam SM,
Wiehe K,
Lu X,
Parks R,
Sutherland LL,
McDanal C,
Perez LG,
Mansouri K ,
Gobeil SMC,
Janowska K,
Stalls V,
Kopp M,
Cai F,
Lee E,
Foulger A,
Hernandez GE,
Sanzone A,
Tilahun K ,
Jiang C,
Tse LV,
Bock KW,
Minai M,
Nagata BM,
Cronin K,
Gee-Lai V,
Deyton M,
Barr M,
Von Holle T,
Macintyre AN ,
Stover E,
Feldman J,
Hauser BM ,
Caradonna TM ,
Scobey TD,
Rountree W,
Wang Y,
Moody MA,
Cain DW,
DeMarco CT,
Denny TN,
Woods CW,
Petzold EW,
Schmidt AG,
Teng IT,
Zhou T,
Kwong PD ,
Mascola JR,
Graham BS,
Moore IN,
Seder R,
Andersen H,
Lewis MG,
Montefiori DC,
Sempowski GD ,
Baric RS,
Acharya P,
Haynes BF,
Saunders KO
(2021) Cell , 184 , 4203 - 4219.e32
,
Manne K,
Martinez DR,
Schafer A,
Alam SM,
Wiehe K,
Lu X,
Parks R,
Sutherland LL,
McDanal C,
Perez LG,
Mansouri K ,
Gobeil SMC,
Janowska K,
Stalls V,
Kopp M,
Cai F,
Lee E,
Foulger A,
Hernandez GE,
Sanzone A,
Tilahun K ,
Jiang C,
Tse LV,
Bock KW,
Minai M,
Nagata BM,
Cronin K,
Gee-Lai V,
Deyton M,
Barr M,
Von Holle T,
Macintyre AN ,
Stover E,
Feldman J,
Hauser BM ,
Caradonna TM ,
Scobey TD,
Rountree W,
Wang Y,
Moody MA,
Cain DW,
DeMarco CT,
Denny TN,
Woods CW,
Petzold EW,
Schmidt AG,
Teng IT,
Zhou T,
Kwong PD ,
Mascola JR,
Graham BS,
Moore IN,
Seder R,
Andersen H,
Lewis MG,
Montefiori DC,
Sempowski GD ,
Baric RS,
Acharya P,
Haynes BF,
Saunders KO
(2021) Cell , 184 , 4203 - 4219.e32
Grant Support: