EMD-22943

Single-particle
3.85 Å
EMD-22943
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Deposition: 04/11/2020
Map released: 16/12/2020
Last modified: 15/12/2021
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Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-22943
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
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Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 5.5

EMD-22943

Single-particle
3.85 Å
EMD-22943
3D View Gallery
Deposition: 04/11/2020
Map released: 16/12/2020
Last modified: 15/12/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: Single ACE2-bound SARS-CoV-2 trimer spike at pH 5.5
Fitted models: 7kne

Deposition Authors: Gorman J , Rapp M, Kwong PD , Shapiro L
Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Zhou T , Tsybovsky Y, Gorman J , Rapp M, Cerutti G , Chuang GY, Katsamba PS , Sampson JM , Schon A, Bimela J, Boyington JC, Nazzari A, Olia AS, Shi W, Sastry M, Stephens T, Stuckey J, Teng IT, Wang P, Wang S, Zhang B, Friesner RA, Ho DD, Mascola JR, Shapiro L , Kwong PD
(2020) Cell Host Microbe , 28 , 867 - 879.e5
PUBMED: 33271067
DOI: doi:10.1016/j.chom.2020.11.004
ISSN: 1934-6069