EMDB EMD-22853

Single particle reconstruction
3.8Å resolution

Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-437 and EBOV-515

Map released:
Overview of EMD-22853
Source organisms:
Fitted atomic model: 7kfh
Primary publication:
Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, Crowe Jr JE, Ward AB
Cell Rep 35 108984-108984 (2021)
PMID: 33852862

Function and Biology Details

Sample name: Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-437 and EBOV-515
Ligand: 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-437 and EBOV-515, Virion spike glycoprotein 1, Antibody Fab EBOV-437 light chain, Virion spike glycoprotein 2, Antibody Fab EBOV-437 heavy chain

Experimental Information Details

Resolution: 3.8Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)