EMDB EMD-22851

Single particle reconstruction
6.6Å resolution

Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-329 and EBOV-515

Map released:
Overview of EMD-22851
Source organisms:
Fitted atomic model: 7kfe
Primary publication:
Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, Crowe Jr JE, Ward AB
Cell Rep 35 108984-108984 (2021)
PMID: 33852862

Function and Biology Details

Sample name: Bundibugyo virus GP (mucin deleted) bound to antibody Fab EBOV-329 and EBOV-515
Ligand: 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: Bundibugyo virus GP (mucin deleted) bound to antibody Fab EBOV-329 and EBOV-515, Antibody Fab BDBV-329, Bundibugyo virus GP (mucin deleted), Antibody BDBV-329 heavy chain, Antibody BDBV-329 light chain, Spike glycoprotein 1, Envelope glycoprotein 2

Experimental Information Details

Resolution: 6.6Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TALOS ARCTICA
Detector: GATAN K2 SUMMIT (4k x 4k)