EMDB EMD-22847

Single particle reconstruction
4.4Å resolution

Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-296 and EBOV-515

Map released:
Overview of EMD-22847
Source organisms:
Fitted atomic model: 7kf9
Primary publication:
Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, Crowe Jr JE, Ward AB
Cell Rep 35 108984-108984 (2021)
PMID: 33852862

Function and Biology Details

Sample name: Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-296 and EBOV-515
Ligand: 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-296 and EBOV-515, EBOV-296 Fab, Ebola virus GP (mucin deleted, Makona strain), Antibody Fab EBOV-296 heavy chain, Virion spike glycoprotein 1, Virion spike glycoprotein 2, Antibody Fab EBOV-296 light chain

Experimental Information Details

Resolution: 4.4Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TALOS ARCTICA
Detector: GATAN K2 SUMMIT (4k x 4k)