EMDB EMD-22841

Single particle reconstruction
4.16Å resolution

Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-43 and ADI-15878

Map released:
Overview of EMD-22841
Source organisms:
Fitted atomic model: 7kew
Primary publication:
Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, Crowe Jr JE, Ward AB
Cell Rep 35 108984-108984 (2021)
PMID: 33852862

Function and Biology Details

Sample name: Complex of Bundibugyo virus GP (mucin deleted) bound to the antibody Fab BDBV-43 and ADI-15878
Ligand: 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: Complex of Bundibugyo virus GP (mucin deleted) bound to the antibody Fab BDBV-43 and ADI-15878, Bundibugyo virus GP (mucin deleted), BDBV-43 Fab, Spike glycoprotein 1, BDBV-43 Fab heavy chain, BDBV-43 Fab light chain, Envelope glycoprotein 2

Experimental Information Details

Resolution: 4.16Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)