EMD-22664

Single-particle
3.78 Å
EMD-22664
3D View Gallery
Deposition: 15/09/2020
Map released: 09/12/2020
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22664
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7k4c summary report (pdf.gz) Map and 7k4c FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor Br-cis-22a

EMD-22664

Single-particle
3.78 Å
EMD-22664
3D View Gallery
Deposition: 15/09/2020
Map released: 09/12/2020
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: sample 1
Fitted models: 7k4c

Deposition Authors: Neuberger A , Nadezhdin KD
Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Bhardwaj R , Lindinger S , Neuberger A , Nadezhdin KD , Singh AK, Cunha MR , Derler I , Gyimesi G , Reymond JL , Hediger MA , Romanin C , Sobolevsky AI
(2020) Sci Adv , 6
PUBMED: 33246965
DOI: doi:10.1126/sciadv.abe1508
ISSN: 2375-2548