Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-22508
SARS-CoV-2 spike in complex with the S2H14 neutralizing antibody Fab fragment (three receptor-binding domains open)
EMD-22508
Single-particle8.5 Å
Deposition: 20/08/2020Map released: 14/10/2020
Last modified: 02/12/2020
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: SARS-CoV-2 spike in complex with the S2H14 neutralizing antibody Fab fragment (two receptor-binding domains open)
Deposition Authors: Park YJ, Tortorici MA, Walls AC, Czudnochowski N, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell G, Veesler D
Sample: SARS-CoV-2 spike in complex with the S2H14 neutralizing antibody Fab fragment (two receptor-binding domains open)
Deposition Authors: Park YJ, Tortorici MA, Walls AC, Czudnochowski N, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell G, Veesler D
Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Piccoli L,
Park YJ 
,
Tortorici MA ,
Czudnochowski N,
Walls AC ,
Beltramello M,
Silacci-Fregni C,
Pinto D,
Rosen LE ,
Bowen JE ,
Acton OJ,
Jaconi S,
Guarino B ,
Minola A,
Zatta F ,
Sprugasci N,
Bassi J,
Peter A,
De Marco A,
Nix JC,
Mele F,
Jovic S,
Rodriguez BF,
Gupta SV,
Jin F,
Piumatti G,
Lo Presti G,
Pellanda AF,
Biggiogero M,
Tarkowski M,
Pizzuto MS ,
Cameroni E,
Havenar-Daughton C,
Smithey M,
Hong D,
Lepori V,
Albanese E,
Ceschi A ,
Bernasconi E ,
Elzi L ,
Ferrari P ,
Garzoni C,
Riva A ,
Snell G,
Sallusto F ,
Fink K,
Virgin HW ,
Lanzavecchia A,
Corti D ,
Veesler D
(2020) Cell , 183 , 1024 - 1042.e21
,
Tortorici MA ,
Czudnochowski N,
Walls AC ,
Beltramello M,
Silacci-Fregni C,
Pinto D,
Rosen LE ,
Bowen JE ,
Acton OJ,
Jaconi S,
Guarino B ,
Minola A,
Zatta F ,
Sprugasci N,
Bassi J,
Peter A,
De Marco A,
Nix JC,
Mele F,
Jovic S,
Rodriguez BF,
Gupta SV,
Jin F,
Piumatti G,
Lo Presti G,
Pellanda AF,
Biggiogero M,
Tarkowski M,
Pizzuto MS ,
Cameroni E,
Havenar-Daughton C,
Smithey M,
Hong D,
Lepori V,
Albanese E,
Ceschi A ,
Bernasconi E ,
Elzi L ,
Ferrari P ,
Garzoni C,
Riva A ,
Snell G,
Sallusto F ,
Fink K,
Virgin HW ,
Lanzavecchia A,
Corti D ,
Veesler D
(2020) Cell , 183 , 1024 - 1042.e21
Grant Support: